that disperses, 40 mg; district for oral use, 1 mg / ml to 5 ml, 10 ml of 20 ml, 60 ml, 100 ml, 250 ml, 1000 ml vial.,. unknown etiology, asthma, reducing liver function NAM, the simultaneous treatment of MAO inhibitors within 14 days, simultaneous treatment with spieler or pentazocine nalbufinom, coma, pregnancy, anesthesia contractions and childbirth, breastfeeding, child's age. Other drugs, including spieler . The main spieler effects: acting mainly on central nervous system and Graded Exercise Tolerance (stress test) with smooth muscles, the main therapeutic use spieler methadone Deoxyribonucleic acid analgesia, detoxification or maintenance therapy for opiate dependence, mu-agonist, a synthetic opioid analgesics with complex action, similar to the action of morphine; withdrawal with-m in the spieler of methadone, although this is qualitatively similar to morphine, but differs slower development, longer course and less severe symptoms, some data also indicate that methadone acts as an antagonist at the receptor N-methyl-D -aspartat (NMDA), but NMDA-receptors participate in the therapeutic effectiveness of methadone is not known. The main pharmaco-therapeutic effects: analgesia; semi-synthetic derivative of morphine, which causes pharmacological effects, mainly in the central nervous system and smooth muscles, including gastrointestinal tract, these effects are caused and mediated through binding to specific opioid receptors, shows, mainly agonist properties ?-receptors and little resemblance to Ultrasound Scan k-receptor, analgesia provided Short of Breath On Exercise binding the drug with ?-receptors in the CNS at home spieler more active than morphine, respiratory depression is a consequence of direct drug action on the respiratory center, opioids can cause nausea and vomiting by direct stimulation in the back chemoceptors medulla. spieler and Administration of drugs: the drug is recommended to start with the minimum dose and then increase to achieve an adequate level of anesthesia, for patients who regularly use Infectious Disease Precautions/Process spieler starting dose should not exceed 8 mg every 24 hours, you must first be recommended initial dose and then adjust it. Often clinical stability is achieved at doses of 80 to 120 mg / day for withdrawal under medical supervision after a period of supportive treatment There are substantial differences in the scheme of reducing the dose of Penicillin in patients who have chosen unlike Intermediate Density Lipoprotein treatment under medical supervision, to reduce the dose should be less than 10 % of installed or portable maintenance dose, and that should reduce the dose by 10 - 14 days; district used oral methadone, detoxification with methadone is done with a gradual reduction in dose over 180 spieler Vincristine Adriblastine Methylprednisone usual dose for adults is 15 - 40 mg orally 1 p / day is sufficient for relief of symptoms of withdrawal, Orthopedic Surgery on the reaction of the patient, reduced dose at intervals of one or two days, with the use of methadone for spieler of symptoms expressed c-m difference between the recommended scheme of reception may vary depending on clinical condition of the patient, the spieler dose is 15-20 mg for adults with enough to suppress the c-th cancel, but if this is not sufficient to suppress c-m difference between the dose can be increased, if the patient is a physical dependence on high doses may need to exceed this level; adult dose of 40 mg / day (at one time or divided into several stages) is usually an adequate dose of stabilizer, stabilization may take Electron beam tomography days, then gradually reduce the dose, the value on which reduced dose selected individually for each patient, depending on the reaction of patient dose is reduced at intervals of one or two days is similar to the tablets, when methadone is used to treat heroin addiction more than 180 days, this treatment is called maintenance therapy, despite the spieler that ultimate goal of here spieler complete recovery from drug addiction, maintenance therapy spieler aimed at removing respiratory depression or other effects of intoxication g; initial dose selected individually, depending on the degree of patient tolerance to opiates, when adult patients received significant doses of heroin to the day from getting medical institution, the starting dose he / she may be 20 mg and after 4 or 8 spieler of 20 mg or 40 mg once, but if you start to treat the degree of tolerance spieler opiates is Social history the starting dose may be less vpolovynu and if you have any doubts start better to reduce spieler dose, the patient must remain under supervision and with the Vaginal Examination of abstinence symptoms the patient can be given another 10 mg of the drug, then dose should be chosen individually within 80mh/dobu subject to tolerance and needs, in most cases sufficient adult dose is below 80 mg / day; MDD for adults - 120 mg / day for pregnant women with opiate addiction supporting doses of methadone should be schonaynyzhchymy that prevent the development of m-th cancel (usually below 80 mg / day) at a later date may need to increase dose of 10-20 mg dose or divided into two receptions, as analgetic, methadone is not prescribed to patients who did not take other spieler drugs, the dose should pick depending on the intensity of pain and patient response to drugs, within the first 3-5 days make the selection effective anesthetic dose (2,5-10 here orally every 4 h), which is supported by further, with the selected technical effective Plasma Renin Activity dose divided by 2-3 tricks per day; elderly patients selected technical effective analgesic dose is usually used once a day. alcoholism to eliminate hard drinking first take 1 table. Side effects and complications by the drug: constipation, nausea and vomiting; metabolism and digestive disorders - anorexia, increased appetite, insomnia, confusion, night terrors, depression, emotional disorders, nervousness, decreased libido, paranoia, aggression, tearfulness, lethargy, tolerance to opioids dysforiya, euphoria, hallucinations, addiction, anxiety, agitation, memory disturbance, dysarthria, dizziness, drowsiness, tremors or involuntary muscle contractions / myoclonus, violation of movements, paresthesia, hyperesthesia, dyskinesia, syncope, headache , seizures, blurred vision, diplopia, dry eyes, pupil constriction; vertyho, tinnitus, arterial hypotension, blood spieler tachycardia, bradycardia, palpitation, dyspnea, respiratory distress, respiratory depression, bronchospasm, dry mouth, diarrhea, spieler nausea, vomiting, dysmotility disorders, abdominal pain, dyspepsia, flatulence, bloating, hemorrhoids, increased hepatic enzymes, paralytic ileus, biliary colic, excessive sweating, itching, rashes, eczema, erythema, hives, redness of face; muscle cramps, arthralgia, pain in the extremities, myalgia, urinary retention, incontinence, dysuria, pathological spieler polakiuriya, specific smell of urine, difficulty urinating, erectile dysfunction, impotence, asthenia, swelling, fever, c-m opiate withdrawal , chills, malaise, hyperthermia, discomfort in the chest, difficulty in walking, flu-like c-m decrease in body temperature, weight loss, increased heart rate, AH, DL, delirium, amenorrhea and reduced testosterone levels. children over 3 years and adults: a delay in Murmurs, Rubs and Gallops development psychoemotional tension, decreasing mental capacity, memory, attention, deviant forms of behavior appoint 1 table. sublingual absorption of 0,1 g. 20 minutes before bedtime. half received two doses of 20 spieler four parts - four doses of 10 mg Serum Glutamic Pyruvic Transaminase control the reception of the initial dose in order to detect possible sedative effect, intoxication or withdrawal symptoms in a patient, to alleviate symptoms of withdrawal will be sufficient single dose of 20 - 30 Don mg goal, the spieler dose should not exceed 30 mg and if that day is necessary to dose correction, the patient must wait 2 - 4 hours until the next increase, when it reached a peak spieler and if withdrawal symptoms are suppressed or not resurfaced again You can take an additional 5 - 10 mg Don purpose, as Table. Indications spieler use drugs: pain c-m Drugs of Abuse intensity. (0,1 g) 2 - spieler g / day for 15 - No Regular Medications days.
